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When, in addition to peripheral fluid overload predominance, there is hyponatremia, the drugs to consider are aquaretics (tolvaptan 15-30mg/d or urea 15-30g/d)

PMCID: PMC4044302 Iwakura H, Takagi T, Inaba H, Doi A, Ueda Y, Uraki S, Takeshima K, Furukawa Y, Ishibashi T, Morita S, Matsuno S, Nishi M, Furuta H, Matsuoka TA, Akamizu T

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